We need a large amount of world first class transnational corporations to realize the Chinese Dream, but these top transnational corporations’growth will be influenced by factors from different kinds of perspectives, like macro, median and micro, which are the growth foundation for top transnational corporations’innovation and internationalization. Using the panel data of seven countries from 1996 to 2011, the paper constructs a national index of top transnational corporations, and empirically analyzes home country’ s effect on the growth of Fortune 500. It reveals that top transnational corporations’growth requires a large amount of their home countries’FDI, comparatively high income as economic base, high competitiveness of export as industrial base, high R&D intensity as innovation base, as well government support and utilization of foreign exchange. The growth of Chinese transnational corporations needs positive policies on internationalization and innovation.