The Belt and Road Initiative(B&R), led by China, jointly with many developing countries, is a “Top-Layout” to push forward economic and trade cooperation in Asia. B&R contributes to the innovation of international economic rules, including innovation of ideas and content. The innovation of the international economic rules of B&R needs international rules completion, involving trade, financial, energy, investment, and dispute settlement rules etc. Meanwhile, domestic law also needs to be amended and improved to support the innovation of the international economic rules of B&R. As an experimental area of domestic economic and trade rules, it is crucial for China (Shanghai) Pilot Free Trade Zone to further promote the innovation of economic and trade rule of law of B&R.