Existing dispute settlement mechanisms are not expected to meet the need of resolving disputes properly and effectively. It is imperative and practical to establish an effective mechanism for resolving investment disputes. For the route selection, an international agreement should be reached through international consultations to create a special“Belt and Road”center for the settlement of investment disputes. At the same time, more oriental cultures like mediation shall be put into the dispute settlement mechanism. To specifically design the mechanism, special attention should be paid to an appeal mechanism, the selection of arbitrators, the transparency issue and other key aspects in accord with the general trend of investment arbitration reform.